IGF-1LONG R3

IGF-1Long R3

IGF1-LR3 is a modified version of insulin-like growth factor 1. The full name of the peptide is insulin-like growth factor-1 long arginine 3 ALIGA-1 derivatives play prominent roles in cell division, cell proliferation, and cell-to-cell communication. Though it has similar effects, IGF-1 LR3 does not adhere to IGF binding proteins as strongly as GF This results in IGF1-LR3 remaining in the bloodstream 120 times longer than IGA-1. IGHI-LR3 gains its prolonged half-life as a result of its structural changes. The peptide is created by adding 13 amino acids to the N-terminal end of IGF-1 and by converting the glutamic acid at position 3 OFCA-1 to an arginine residue. The consequences of these modifications are that IGF-1 LR3 retains the pharmacological activity of IGF-1 as an IGF-1 receptor agonist, has a very low affinity for insulin-like growth factor binding proteins (IGFBPs) and metabolic stability. As a result, it is approximately three times stronger than IGF-1 and has a significantly longer half-life of about 20-30 hours (with respect to the half-life of IGF-1-12-15 hours).

Sequence: MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGPYPNK PTGYGSSSRR APQTGIVDEC CERSCDLRRL EMYCAPLKPA KSA

Molecular Formula: C400H625N111011559

CAS Number: 946870-92-4

Appearance      White powder

Purity (HPLC)     >95%

Store at Coo dry place (-20°C. away From the light)

Dose and administration:

IGF-1LR3 is a fine white powder in a vial to be mixed with bacteriostatic water. The powder should be stored in dry and cool places without direct sunlight. The solution should be used with subcutaneous injection into the body fat using a very small insulin needle. Once combined in the solution, the serum should be stored in a refrigerator (between 2 and 8 ° C / 36 ° F and 46 ° F) because the amino acid chain is likely to disintegrate and this may affect its effectiveness. The usual doses of IGF-1LR3 may vary dramatically. It is not unusual to administer 50 micrograms or more per day. However, this may be a little more and even more than necessary to achieve good results. In most cases, 15 micrograms per day with a slight periodic increase if necessary is absolutely sufficient. The overall use of IGF-1LR3 as all IGF hormones is usually 3-4 weeks.