{"id":1603,"date":"2024-04-09T05:18:08","date_gmt":"2024-04-09T10:48:08","guid":{"rendered":"https:\/\/www.medigloballabs.com\/?page_id=1603"},"modified":"2024-04-09T05:18:39","modified_gmt":"2024-04-09T10:48:39","slug":"fk-780","status":"publish","type":"page","link":"https:\/\/www.medigloballabs.com\/?page_id=1603","title":{"rendered":"FK-780"},"content":{"rendered":"<p><strong>Mecasermin [ IGF-1]<\/strong> 4 mg, \u00a0solution for injection<\/p>\n<p><em>Each ml contains 400 mcg of mecasermin*.<br \/>\nEach 10 ml vial contains 4 mg of mecasermin*.<\/em><\/p>\n<p>&nbsp;<\/p>\n<p>Solution for injection.<\/p>\n<p>Mecasermin is a somatomedin C or human\u00a0<em>insulin-like growth factor-1<\/em>\u00a0(rhIGF-1) produced by recombinant DNA technology.\u00a0IGF-1 consists of a chain of 70 amino acids, with three intramolecular disulfide bonds and a molecular weight of 7,649 Da.\u00a0The amino acid sequence of this product is identical to that of endogenous human IGF-1.\u00a0<em>The rhIGF-1 protein is synthesized by the E. coli<\/em>\u00a0bacteria\u00a0previously modified by introduction of the gene encoding human IGF-1.<\/p>\n<p>IGF-1 is the main hormonal mediator of stature growth.\u00a0Under normal circumstances, growth hormone (GH) normally binds to its receptor in the liver and other tissues and stimulates the synthesis\/secretion of IGF-1.\u00a0In target tissues, the IGF-1 type 1 receptor, similar to the insulin receptor, is activated by IGF-1, triggering the transmission of intracellular signals stimulating multiple processes causing of stature growth.\u00a0The metabolic effects of IGF-1 include stimulating the absorption of glucose, fatty acids and amino acids allowing metabolism to support tissue growth.<\/p>\n<p><em><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-1606\" src=\"https:\/\/www.medigloballabs.com\/wp-content\/uploads\/2024\/04\/fk.png\" alt=\"\" width=\"400\" height=\"437\" srcset=\"https:\/\/www.medigloballabs.com\/wp-content\/uploads\/2024\/04\/fk.png 400w, https:\/\/www.medigloballabs.com\/wp-content\/uploads\/2024\/04\/fk-275x300.png 275w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/em><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mecasermin [ IGF-1] 4 mg, \u00a0solution for injection Each ml contains 400 mcg of mecasermin*. Each 10 ml vial&hellip;<a href=\"https:\/\/www.medigloballabs.com\/?page_id=1603\" class=\"more-link\"><span class=\"more-button\">Continue reading<span class=\"screen-reader-text\">FK-780<\/span><\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1603","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.medigloballabs.com\/index.php?rest_route=\/wp\/v2\/pages\/1603","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.medigloballabs.com\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.medigloballabs.com\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.medigloballabs.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.medigloballabs.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1603"}],"version-history":[{"count":4,"href":"https:\/\/www.medigloballabs.com\/index.php?rest_route=\/wp\/v2\/pages\/1603\/revisions"}],"predecessor-version":[{"id":1608,"href":"https:\/\/www.medigloballabs.com\/index.php?rest_route=\/wp\/v2\/pages\/1603\/revisions\/1608"}],"wp:attachment":[{"href":"https:\/\/www.medigloballabs.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1603"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}